Integrated Biomedical Sciences Seminar: Mary Anne O'Connell
fre
19
sep
Fredag 19 september, 2025kl. 14:00 - 15:00
5B P6 Stora hörsalen, NUS
The essential role of the RNA editing enzyme, Adar1 in immunity
Talare: Mary Anne O'Connell, Central European Institute of Technology (CEITEC), Masaryk University, Czechia
Värd: Francesca Aguilo, Institutionen för molekylärbiologi
Om föreläsningen: The RNA editing enzyme adenosine deaminase acting on RNA 1 (ADAR1) modifies double-stranded (ds) RNA by deaminating adenosine to inosine (A-to-I). Inosine in dsRNA helps the cell to distinguish self from non-self RNA thus preventing aberrant activation of the dsRNA antiviral immune sensors. ADAR1 also can have protein-protein interactions with Protein Kinase R (PKR) another dsRNA sensor to prevent its activation. We have expanded our study of ADAR1 and now observe that it also plays an important role in adaptive immunity.
Hitta hit: Föreläsningssalen 5B P6 Stora hörsalen ligger i sjukhusets lokaler. Mazemap-länken för hörsalen är
Integrated Biomedical Sciences Seminars är en bred, öppen seminarieserie inom life science.